Manga with Sci-Fi genre:

Akatoki Hoshi Residence

On one side, we have a guy living a boring and meaningless life meets Touko, a pretty girl, and it turns his life around. They get married, but three months later she tells him she is an alien from a far away planet, and that she must return to her home planet in a few days. Is she making excuses? Is she really an alien? Will he let their marriage end so easily? On the other side we have Honda Haruno, a girl which has absolutely no other recollection other than being "sent" by her superiors to gather information about humanity; as a secret agent she needs to do her best as to learn as much as she can about society without giving away her true nature…. However on her first day of school she meets this boy "Isuzu", who has extensive information about UFOs, invaders from other space & related topics… Haruna not only is surprised to see that her cover has been blown out right from the start, but also she must know how this Isuzu fellow knew about her. Even though they don't realize it; Haruna and Touko are actually neighbors in the Akatoki Hoshi Residence… but, is this all? Well, you have no way to know exactly how mysterious is the people of the Akatoki Hoshi Residence until you step forward and read it out.

4.2 (93)

Chapter 6.5

8 years ago
Sci-Fi Romance Drama Slice of Life
Hagane

When forcibly injected with the DNA of Musashi—the legendary swordsman—by the "Akai Umi" (Red Sea) secret organization, Hagane Yakushimaru becomes a master fencer with supernatural powers. She sets off to rescue her parents who have been abducted by Akai Umi, making friends and foes with supernatural beings (parasite projects) who have also been injected with the DNA of other historical figures. What is Hagane's secret? Why is she the only successful female DNA injection? What exactly is the project called the "Revelations of the New Millennium"?

4.0 (12)

Chapter 38

8 years ago
Sci-Fi Action Psychological Comedy Drama
Chirality

In a not-too-distant future, the Earth has been overrun by a horrifying technovirus. Mechanical parasites, mistakenly created in an attempt to advance technology, attach themselves to human spinal cords and turn their hosts into cyborgs. Desperate to rid themselves of this technological terror, the remaining human survivors must band together and learn to defend themselves against their android enemies.

3.7 (92)

Chapter 21

8 years ago
Genderswap Sci-Fi Action Girls Love
Betterman

A manga adaption of the Betterman anime.

2.9 (7)

Chapter 6

8 years ago
Sci-Fi Action Psychological Mecha Mystery
Yagyu Jubei Dies

Now… Jubei Yagyu is the head of the Yagyu Clan following the events of Demonic Resurrection and has mostly retired from the world. A group of warriors decide to ask him if he wants to take over a post at their dojo, but Jubei is more interested in watching the Noh of his friend and subordinate Chikuami. Yagyu Jubei Dies is the third in Futaro Yamada's Jubei Trilogy that began with The Yagyu Ninja Scrolls and continued in Makai Tensho/Demonic Resurrection.

3.7 (10)

Chapter 23

8 years ago
Thriller Sci-Fi Historical Action Psychological Adventure Drama Tragedy
Susano-o

Plot revolves around high school freshman Shingo Susa as he is invited by his crush from middle school Sayuri Shiroyuki to the school's supernatural club. Over the course of the series Susa begins to gain supernatural powers, something that prodigy Rei Uryu, attempts to awaken to bring out the psychic giant, Susano Oh to destroy humanity and establish a new world order. --- - **Won the 4th Kodansha Manga Award for Shonen in 1980**

3.6 (24)

Chapter 57

8 years ago
Award Winning Demons Mafia Sexual Violence Gore School Life Delinquents Supernatural Sci-Fi Action Crime Sports Drama Tragedy
Transistor Venus

It's the year 2269, and April Enus is working as a spy for the Alliance. She's known as "Venus" because of her special power: fatalities don't seem to happen when she's around. But is this power a blessing or a curse?

3.9 (40)

Chapter 56

8 years ago
Sci-Fi Action Comedy Adventure Girls Love
Ragnarock City

Reichieru has just moved to Ragnarock City, where she is attending the St. Freyr School. But, will she be able to cover up her special secret while adapting to the fashion of the modern city? Note: The original serialization was mostly monochrome with some pages being printed copies of animation cels. The volume release is fully colored. The mangaka also added pubic hair, which was not present in the magazine release.

3.7 (110)

Chapter 6.5

8 years ago
Sci-Fi Girls Love
Devilman vs Getter Robo

Akira and Miki from Devilman are visiting the Getter Robo base when it happens to be attacked. But who are the attackers? The demon Silene has joined with the Dinosaur Empire! Will our heroes prevail?!

3.2 (29)

Chapter 4

8 years ago
Sci-Fi Action Mecha
Keep on Vibrating

A short story collection from Jirō Matsumoto (the artist of "Freesia"). Contains explicit sexual imagery and language, not recommended for the squeamish.

3.6 (211)

Chapter 7

8 years ago
Thriller Sci-Fi Action Psychological Romance Crime Drama Horror Slice of Life Tragedy
Velveteen & Mandala

The story centers around Becchin, a high school girl who lives in a battle tank on a riverbed in Tokyo's Suginami ward, and her friend Mandara. Together, the two exterminate the zombies of dead Suginami citizens.

3.3 (209)

Chapter 14.2

8 years ago
Thriller Sci-Fi Action Psychological Comedy Adventure Philosophical Drama Medical Horror Slice of Life Mystery Tragedy
FLCL

Naota is a normal Japanese sixth grader (although a little cynical), but when his older brother leaves for America to play baseball he leaves his homeless 17 year old girlfriend Mamimi behind. Mamimi is sending mixed signals and advances to Naota, and he doesn't know what to do about her. But to make matters worse, Naota's world is totally turned upside down when he is run over by a woman on a Vespa. During their first encounter, she hits him over the head with her guitar, which then causes a horn to grow out of his forehead. She calls herself "Haruko" and her presence changes Naota's life to even further insanity. [Official English](https://www.darkhorse.com/Books/18-934/FLCL-Omnibus-TPB)

4.1 (281)

Chapter 7.2

8 years ago
Thriller Sci-Fi Action Psychological Romance Comedy Mecha Crime Philosophical Drama Slice of Life Tragedy
SCATTER - Wish You Were Here

From the author of [The World is Mine](https://mangadex.org/manga/6002/). A young, unemployed, seemingly unmotivated young man is moving through his life. As a teenager, he and some of his friends formed a "Boyz 4 Men" club, which was based on a hatred of sex and women. As arguably the most opinionated member, his view of sexuality as an adult is far from normal. After a highly sexual encounter in a park at night, he has decided to attempt to draw perverted fetish manga. This brings him once again to the presence of a woman from the park, Sawada Kazumi. She's a manga editor and single mother with a perverted and intense personality of her own. What will happen when their worlds collide?

2.7 (23)

Chapter 6

8 years ago
Sci-Fi Psychological Drama
Heavy Metal Warrior Xenon

A dramatic story set in contemporary Japan, about a guy with amnesia, who finds out he was turned into a super-cyborg in a corporate weapon research program. He goes on a mission of revenge. A little shallow, perhaps, but a good example of shounen SF/action manga. The manga ended abruptly, because the magazine it was being serialized in changed its target public and it was decided that Xenon didn't fit in anymore.

4.3 (8)

Chapter 29

8 years ago
Sci-Fi Fantasy
UFO Robo Grendizer

A short manga version of the UFO Robo Grendizer anime. Released along the anime series, UFO Robot Grendizer follows the adventures of Duke Fleed, the prince of Planet Fleed, who, disguised as Daisuke, a farm worker, fights against the forces that destroyed his planet, the Vegan Empire, also the creators of Grendizer that Duke stole to fight them. While not originally considered part of the Mazinger series, Koji Kabuto and the Mazinger mechas appear in this series, making it sort of a sequel. Grendizer introduced the concept of a transformable robot and a space mecha, concepts that were later taken into other mecha series. It was extremely popular in Japan, Canada, France, Italy, and the Arab world and has a strong following in those countries even today.

3.5 (42)

Chapter 5

8 years ago
Monsters Survival Military Gore Aliens Thriller Sci-Fi Action Comedy Mecha Adventure Drama Fantasy
UFO Robo Grendizer (Outa Gosaku)

UFO Robot Grendizer is the third entry in the Mazinger Trilogy by Go Nagai, following Mazinger Z and Great Mazinger. This particular incarnation was illustrated by Gosaku Ota and published in Boken Oh, Otomodachi from October 1975 – March 1977. It follows the adventures of Duke Fleed, the sole survivor of an attack on the Vegan Empire, who defends his second home, the Earth, from the Vegan attack, together with the giant robot Grendizer.

3.8 (14)

Chapter 12

8 years ago
Monsters Survival Aliens Thriller Sci-Fi Action Mecha Adventure Drama Fantasy
Hen na Nee-san

A series of unrelated slightly erotic short stories… or is it?

3.9 (553)

Chapter 11

5 years ago
Sci-Fi Comedy Girls Love
Yasha (YOSHIDA Akimi)

Arisue Sei lived as happily as any normal kid would, just him and his mother – a particularly private woman – on an outlying island of Okinawa. There were also his friends Toichi and Moichi. The only unusual things about Sei were his sharp instincts and high intelligence. But everything changed when his mother was killed and he was kidnapped by the people of Neo Genesis. Now, six years after the kidnapping, Arisue Sei has returned to Japan with the title of "Doctor" at only the age of 18, and he's not the Sei that his friends remember. There are bodyguards with him who protect him from others who wish to possess his superb intellect. He says he's come back to assist with the research at Rakuhoku University, where Moichi now works, but here is where the door to Sei's secrets just begins to open… --- - **Won the 47th Shogakukan Manga Award for Best Shojo in 2002**

4.4 (53)

Chapter 63

8 years ago
Sci-Fi Action Crime Drama Mystery
Newmanoid CAM

In the face of growing intensification of heinous crimes committed annually, an abundant number of victims follow one after the other, even as a result of the police, who should be keeping public order in towns. Accordingly, it was devised that man and beast would be genetically combined to oppose those who commit heinous crimes: this new race with multiple strength increases were called "Newmans." From there, that technology was further utilized, and artificial life forms called "Newmanoids" were produced. Included one-shots in Volume 2: Bed no Naka no Armageddon (Armagedon Inside the Bed), Neko to Oni-san, Ganbare Konomi-chan, Princess Education! Source: MU

2.4 (19)

Chapter 22

8 years ago
Sci-Fi Action Girls Love
Memories of Emanon

Based on the award-winning novel by Shinji Kajio, Memories of Emanon tells the story of a mysterious girl who holds a 3-billion-year old memory, dating back to the moment life first appeared on Earth.

4.4 (1598)

Chapter 9.5

8 years ago
Sci-Fi Historical Psychological Drama Slice of Life Mystery
Tomorrows Thief

Kyouichi Miyasako is the star employee at his company. Why does he work so hard? He doesn’t know either. What he does know is that he sorely misses his girlfriend… the one he broke up with in college because he couldn’t put up with her hobbies any further. One day, an ominous black sphere mysteriously appears in the skies and shoots a laser beam in his direction. He doesn’t get hit, of course, but when the smoke clears, guess who he sees?

3.9 (736)

Chapter 30.5

8 years ago
Thriller Sci-Fi Action Romance Comedy Philosophical Drama Mystery
Assembler OX

In A.D. 1997. Having failed to conquer the Earth, Compiler and Assembler from Another World settle down in the residence of Nati and Toshi Igarashi whom they choose as their partners. As they start their literally unworldly community life, various Sudaran assassins arrive from Another World one after another to attack Compiler and Assembler, until, in good time, all of those begin to turn into old memories… Yes, in 2000, the last year of the century, Assembler has started to lead quite a different life — a life as a "human being"…

4.3 (2)

Chapter 3

8 years ago
Sci-Fi Romance Comedy Drama
El Shaddai - Another Story: Exodus

Adapted from the 2011 video game El Shaddai: Ascension of the Metatron by IGNITION. The events of this story take place before the game, following the chosen priest Enoch, freshly summoned from Earth by God to serve as a clerk in Heaven, is thrust into the world of Heaven, where not everything is what it seems. A conspiracy is brewing in Heaven, and the only one on his side is an angel by the name of Lucifel…

2.5 (1)

Chapter 13

8 years ago
Sci-Fi Historical Drama
The Affairs of the Universe

A oneshot from Monthly Garo 1966-08.

Oneshot Aliens Music Sci-Fi Comedy Drama Slice of Life